Dopaminergic stimulation in unilateral neglect

Dopaminergic stimulation in unilateral neglect.

OBJECTIVE To explore the hypothesis that dopaminergic circuits play a part in the premotor components of the unilateral neglect syndrome, the effects of acute dopaminergic stimulation in patients with neglect were studied. METHODS Two tasks were evaluated before and after subcutaneous administration of apomorphine and placebo: a circle crossing test and a test of target exploration (a modifie...

Swan Unilateral Spatial Neglect

Beyond unilateral neglect.

When required to set the endpoints of an imaginary horizontal line of a given length on the basis of its midpoint printed on a sheet of paper, left neglect patients most frequently misplaced endpoints leftwards. Though giving rise to the very same disproportion usually found with these patients on canonical line bisection tasks, this behaviour cannot be accommodated by current explanations of u...

Assessment of unilateral neglect.

U nilateral neglect (ULN) (or “neglect”) is a common behavioral syndrome in patients following stroke. The reported incidence of ULN varies widely from 10%1 to 82%2 following right-hemisphere stroke and from 15%3 to 65%2 following left-hemisphere stroke. Reasons for the variability in the published rates of occurrence of ULN after stroke include subject selection criteria, lesion site, and the ...

Revisiting unilateral neglect.

Unilateral neglect, a neurological disorder in which patients fail to detect or respond to contralesional stimuli, has long been considered a failure of attentional orienting mechanisms. This review provides a selective overview of the prominent biases in spatial orienting and exploratory motor behaviour observed in these patients before considering the impact of other factors on the presentati...